Drug & Substance Guide
Over the Counter Drugs
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What over-the-counter drug abuse is
Over-the-counter drugs are medications sold without a prescription, and some of them contain active ingredients that make them likely to be abused.
More than 750,000 retail outlets in the United States sell them, and 8 in 10 consumers use them to relieve symptoms without seeing a doctor.
What makes them easy to misuse is not the chemistry. They are widely available, inexpensive and legal, with no age requirement and no limit on how much can be bought at once.
- What they are
- Medications sold without a prescription
- How widely sold
- More than 750,000 U.S. retail outlets
- How widely used
- 8 in 10 consumers
- Why misuse is easy
- Cheap, legal, no age limit, no purchase cap
Legal and harmless are different words. If an over-the-counter habit has got away from you, it is still treatable.
Although current national data doesn’t offer a full picture on the scope of the OTC drug abuse problem in America, the Substance Abuse and Mental Health Services Administration (SAMHSA) reported that about 3.1 million people (ages 12 to 25) used OTC cold and cough medicines to get high.2
Over the counter drugs are safe and effective when they are used properly as directed on the box, but when they are misused by taking higher or more frequent doses than necessary, they can cause physical harm, tolerance, dependence, or addiction.
What is OTC Drug Abuse?
OTC drug abuse has increased in recent years, especially among teenagers and young adults.2,3 Many people will abuse OTC drugs to self-medicate symptoms at home or to get high. Common signs of OTC drug abuse include:
- Mood swings
- Memory lapses
- Changes in appetite and sleeping patterns
- Lack of interest in hobbies and regular activities
- Empty medicine bottles in the trash
- Disappearing medication from the medicine cabinet
- Regular large purchases of OTC medications when it’s not necessary
The misuse of over the counter drugs can lead to serious physical health problems, dependence, and addiction. Although OTC drugs can be addictive, other prescription drugs and illegal substances are more potent. A person who is misusing OTC drugs may be more likely to move on to other drugs like prescription painkillers or marijuana in search of a stronger high.
What Are Some Commonly Abused Over the Counter Drugs?
Any use of an OTC medication that is outside of what is medically recommended is considered abuse. Here are some of the most commonly abused over the counter drugs in the U.S.
Cough and cold medicine (Dextromethorphan/DXM and Pseudoephedrine)
OTC cough medicines like Nyquil can produce a high and hallucinations when they are abused. Dextromethorphan (DXM) is an active ingredient found in cough medicines, which can also cause several harmful side effects when taken in large doses. High doses of DXM can cause:
- Nausea and vomiting
- Dizziness
- Hot flashes
- Sweating
- Lethargy
- Coordination problems
- Panic attacks
- Seizures
- Hallucinations
- Impaired judgment and cognition
- Hyperactivity
- Slurred speech
- Dissociation from body
- Increase blood pressure
- Rapid eye movement
- Skin rashes
- Racing heartbeat
- Euphoria
- Paranoia
- Disorientation
- Feelings of floating
- Altered perception of time4
The misuse of cough medicine is often called “robo-tripping,” “skittling” or “dexing.”
The active ingredient in many cold medicines, pseudoephedrine, can produce stimulant effects and hallucinations when it is abused.5 Pseudoephedrine can also easily be chemically converted to methamphetamine (meth) and crystal meth.6
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OTC Drug Street Names
Certain slang terms or street names may be used to refer to some of the commonly abused over the counter medications listed above.
| Street Names/Slang Terms for OTC Drugs | |
| Dextromethorphan | DXM, dextro, drix, poor man’s ecstasy, red devils, robo, triple C, Tussin, X |
| Dimenhydrinate | Dime tabs, dime, substance D |
| Loperamide | Poor man’s methadone |
| Pseudoephedrine | Chalk, crank, meth, speed |
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Understanding Over-the-Counter (OTC) Drugs: Common Questions and Misuse Risks
What are examples of OTC stimulants?
Some over-the-counter (OTC) stimulants include caffeine pills, pseudoephedrine found in cold medicines, and certain weight-loss supplements. These drugs are easily available but may be misused for energy or appetite suppression.
What does OTC mean for drugs?
OTC stands for “over-the-counter.” It refers to medications you can buy without a doctor’s prescription, such as pain relievers, allergy medicines, cough syrups, and motion sickness pills.
Which drugs are OTC drugs?
Common OTC drugs include acetaminophen (Tylenol), ibuprofen (Advil, Motrin), cough suppressants with dextromethorphan (DXM), antihistamines, and gastrointestinal medicines like loperamide (Imodium).
What is the most popular OTC drug?
Acetaminophen is one of the most widely used OTC drugs for pain and fever relief. Ibuprofen and cold medicines containing DXM are also highly popular.
What is the most commonly used OTC drug?
Pain relievers like acetaminophen and ibuprofen top the list of the most commonly used OTC drugs worldwide.
What OTC drugs can be misused?
Cough medicines containing DXM, antihistamines such as diphenhydramine, and anti-diarrheal drugs like loperamide are among the most misused OTC medications, often taken in high doses for hallucinogenic or sedative effects.
What drug is most commonly abused?
While illicit drugs lead in abuse overall, among OTC medications, DXM and loperamide are most frequently misused due to their psychoactive or opioid-like effects when taken in excess.
Is DXM an opioid?
No, dextromethorphan (DXM) is not an opioid. It is a cough suppressant found in many OTC cold medications. At high doses, however, it can produce dissociative effects similar to hallucinogens.
What type of drug is DXM?
DXM is classified as a cough suppressant and antitussive medication. It works on the brain to reduce the urge to cough but may cause dangerous side effects when abused.
Why is DXM legal?
DXM remains legal because it is effective for treating coughs and is safe when used as directed. Abuse occurs only when individuals consume large amounts outside recommended guidelines.
What is an example of an over-the-counter drug?
An over-the-counter drug is any medication you can buy in a store without a prescription, and the page notes the scale: more than 750,000 retail outlets in the U.S. sell them, and 8 in 10 consumers use them rather than see a doctor. Some contain active ingredients that make them more likely to be abused, and the page lists what makes that easy: they are widely available, inexpensive, legal, and carry no age requirement or purchase limit. Misuse can lead to dependence and addiction, and people who misuse OTC drugs are more likely to move on to prescription painkillers or other drugs for a stronger high.
Learn More About OTC Addiction and Abuse
- Dextromethorphan (DXM)
- Imodium
Pseudoephedrine
Pseudoephedrine is a decongestant. It shrinks blood vessels in the nose to relieve...
References
References:
- aafp.org: Afp
- monitoringthefuture.org: Monographs (PDF)
- cesar.umd.edu: DXM
- everydayhealth.com: Pseudoephedrine
- PubMed: 29684907
- https://www.knowyourotcs.org/ingredient/loperamide/
- regulations.gov: Document
- PubMed: 26985532
- NIDA: Over counter medicines
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